Protein Details: Aquaporin PIP1-1

Protein ID

ICDB_Pro_1742

Protein Name

Aquaporin PIP1-1

Gene Name

PIP1-1

Organism

Musa acuminata (Banana) (Musa cavendishii)

Length

286 amino acids

AlphaFoldDB

AF-S5ZH89-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across cell membrane; mercury-insensitive (By similarity). Promotes primary root elongation and root hair formation . Contributes to the tolerance to multiple abiotic stresses including salt (NaCl); cold and water deprivation; by modulating cytosolic K(+)/Na(+) ratio; maintaining osmotic balance; and reducing membrane injury (e.g. oxidative injury) . Regulates also the expression of abscisic acid (ABA)-responsive genes during dehydration and salt stresses .

Sequence

MEGKEEDVRLGANKFSERQPIGTAAQSDKGYKEPPPAPLFEPGELTSWSFYRAGIAEFMATFLFLYITILTVMGVVKSNSKCSTVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRALFYMVMQCLGAICGAGVVKGYQKGLYESNGGGANVVAPGYTKGDGLGAEIVGTFILVYTVFSATDAKRNARDSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKKHAWDDHWIFWVGPFIGAALAAIYHQIVIRAIPFKSRP

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed in leaves; roots; stems; flowers and fruits; with highest levels in roots

DOI ID

10.1186/1471-2229-14-59; 10.3390/ijms160819728; 10.3389/fpls.2021.699230; 10.3389/fpls.2021.780544